Is there any operational overhead (apart from disk storage) penalty from having unused perl packages installed? (I've googled around, but have not found any real answer.)

In other words, for sandbox use, looking at all versions say from 3.8 up, should unused packages be removed for testing comparative efficiency, speed, etc of a single version?

Are there any packages where "older" perl is required for "older" Koha?

If not (and I get the impression that there is probably nothing detrimental), is there a "master" list of all perl modules across the Koha spectrum?  Or is this an impossible dream?